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Is an iris claw IOL a good option for correcting surgically induced aphakia in children? A review of the literature and illustrative case study

机译:虹膜爪IOL是否适合纠正儿童手术引起的无晶状体?文献综述和说明性案例研究

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摘要

Refractive correction of aphakia in childhood can be a complex management issue following lensectomy for congenital cataract or ectopia lentis. Some children have inadequate capsular support to allow an ‘in the bag’ or sulcus fixated intra-ocular lens (IOL). In such cases, options for refractive correction include spectacles, contact lenses or surgically fixed IOLs. Many methods of intra-ocular IOLs fixation have been described and none widely adopted in children. In recent years, the iris fixated Artisan Aphakic IOL (Ophtec BV, Groningen, The Netherlands) has gained popularity but there is still significant concern about the rate of corneal endothelial cell loss and IOL de-enclavation. Here, we review the current literature on the use of iris fixated IOLs in children, the published data on endothelial cell loss and deenclavation rates. We present a case illustrating the significant improvements in quality of life which can be seen in selected children but also the rate of endothelial cell loss which can be encountered after initial surgery and a re-enclavation event. We make the case that until more data is available on normal endothelial cell decline in early childhood in addition to age specific rates of endothelial cell loss and deenclavation rates following surgery, the use of iris fixated IOLs in children will continue to be a moot point and is unlikely to be widely adopted.
机译:对于先天性白内障或轻度外翻,在晶状体摘除术后,对儿童无晶状体进行屈光矫正可能是一个复杂的管理问题。一些孩子的囊膜支持不足,无法“固定”或固定沟内人工晶状体(IOL)。在这种情况下,屈光矫正的选择包括眼镜,隐形眼镜或手术固定的IOL。眼内人工晶状体固定的方法很多,在儿童中还没有广泛采用。近年来,虹膜固定的Artisan Aphakic IOL(Ophtec BV,格罗宁根,荷兰)获得了普及,但人们仍然非常关注角膜内皮细胞丢失和IOL脱发的速度。在这里,我们回顾了有关在儿童中使用虹膜固定IOL的最新文献,有关内皮细胞损失和去粘连率的公开数据。我们提供了一个病例,说明在选定的儿童中可以看到生活质量的显着改善,但是在初次手术和再次包埋事件发生后,内皮细胞的损失率也可能会提高。我们认为,除非有更多的关于儿童早期正常内皮细胞下降的数据,除了特定年龄的内皮细胞丢失率和手术后的去粘毛率,否则在儿童中使用虹膜固定的人工晶状体将继续成为争论的焦点,并且不太可能被广泛采用。

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